Jesus H Murphy
A light exclamation of shock or exasperation, for when plain Jesus won't cover it. Stretch it to Jesus Murphy O'Toole for real emergencies.
Also spelt Jesus Murphy O'Toole
Jesus H Murphy, would ye look at the price of a pint in dat place!

Shall I translate it into posh English for you, boi?
Well, hello there. Here it is in posh English.
Merciful heavens, do observe the price of a pint of stout in that establishment!
Questions
What does Jesus H Murphy mean in Ireland?
A light exclamation of shock or exasperation, for when plain Jesus won't cover it. Stretch it to Jesus Murphy O'Toole for real emergencies.
How do you use Jesus H Murphy in a sentence?
“Jesus H Murphy, would ye look at the price of a pint in dat place!”
Updated
On the list: Irish slang phrases